However, it contains four Ig domains similarity to other insect hemolins. The deduced amino acid of CmHem has relatively low identities (41.9–62.3%) to various insect hemolins. The cDNA of CmHem was 1,515 bp in length and encoded 408 amino acids. medinalis ( CmHem) was cloned and sequenced. Further, the complete hemolin sequence of C. medinalis was reassembled from the transcriptome. A 1,528 bp contig as potential hemolin-like gene of C. In this study, the hemolin-like gene from a Crambidae insect, Cnaphalocrocis medinalis, CmHem was cloned, and its role in insect development and baculovirus infection was analyzed. However, the innate immune response of hemolin to baculovirus infection varies among different insects. PeerJ 11: e16225 Īs a member of the immunoglobulin superfamily, hemolins play a vital role in insect development and defense against pathogens. CmHem, a hemolin-like gene identified from Cnaphalocrocis medinalis, involved in metamorphosis and baculovirus infection. Cite this article Han G, Li C, Zhang N, Liu Q, Huang L, Xia Y, Xu J. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited. Licence This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. Lixiahe District Institute of Agricultural Sciences in Jiangsu, Yangzhou, China DOI 10.7717/peerj.16225 Published Accepted Received Academic Editor Srinivas Sistla Subject Areas Agricultural Science, Entomology, Molecular Biology, Zoology Keywords Hemolin, Metamorphosis, Immune recognition, Infection, Cnaphalocrocis medinalis Copyright © 2023 Han et al.
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